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Synthesis of Bacillithiol and the Catalytic Selectivity of FosB-type Fosfomycin Resistance Proteins

[Image: see text] Bacillithiol (BSH) has been prepared on the gram scale from the inexpensive starting material, D-glucosamine hydrochloride, in 11 steps and 8-9% overall yield. The BSH was used to survey the substrate and metal-ion selectivity of FosB enzymes from four Gram-positive microorganisms...

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Autors principals: Lamers, Alexander P., Keithly, Mary E., Kim, Kwangho, Cook, Paul D., Stec, Donald F., Hines, Kelly M., Sulikowski, Gary A., Armstrong, Richard N.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544479/
https://ncbi.nlm.nih.gov/pubmed/23030527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302327t
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