Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus

[Image: see text] The Gram-positive pathogen Staphylococcus aureus is a leading cause of global morbidity and mortality. Like many multi-drug-resistant organisms, S. aureus contains antibiotic-modifying enzymes that facilitate resistance to a multitude of antimicrobial compounds. FosB is a Mn(2+)-de...

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Detalhes bibliográficos
Main Authors: Thompson, Matthew K., Keithly, Mary E., Goodman, Michael C., Hammer, Neal D., Cook, Paul D., Jagessar, Kevin L., Harp, Joel, Skaar, Eric P., Armstrong, Richard N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985756/
https://ncbi.nlm.nih.gov/pubmed/24447055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4015852
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