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Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer

The inhibitor of DNA-binding (Id) proteins, Id1–4 are negative regulators of basic helix-loop-helix (bHLH) transcription factors. As key regulators of cell cycle and differentiation, expression of Id proteins are increasingly observed in many cancers and associated with aggressiveness of the disease...

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Autors principals: Sharma, Pankaj, Chinaranagari, Swathi, Patel, Divya, Carey, Jason, Chaudhary, Jaideep
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544455/
https://ncbi.nlm.nih.gov/pubmed/23342267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.16
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