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EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer

Inhibitor of DNA binding/differentiation protein 4 (ID4) is dominant negative helix loop helix transcriptional regulator is epigenetically silenced due to promoter hyper-methylation in many cancers including prostate. However, the underlying mechanism involved in epigenetic silencing of ID4 is not k...

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Detalhes bibliográficos
Main Authors: Chinaranagari, Swathi, Sharma, Pankaj, Chaudhary, Jaideep
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196193/
https://ncbi.nlm.nih.gov/pubmed/25115397
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