Overexpression of Snail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cells

Epithelial–mesenchymal transition (EMT) is a critical process providing tumor cells with the ability to migrate and escape from the primary tumor and metastasize to distant sites. Recently, EMT was shown to be associated with the cancer stem cell (CSC) phenotype in breast cancer. Snail is a transcri...

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Bibliographische Detailangaben
Hauptverfasser: Fan, Fan, Samuel, Shaija, Evans, Kurt W, Lu, Jia, Xia, Ling, Zhou, Yunfei, Sceusi, Eric, Tozzi, Federico, Ye, Xiang-Cang, Mani, Sendurai A, Ellis, Lee M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2012
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544430/
https://ncbi.nlm.nih.gov/pubmed/23342249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.4
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