Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression

Aberrant activation of a latent embryonic program - known as the epithelial-mesenchymal transition (EMT) - can endow cancer cells with the migratory and invasive capabilities associated with metastatic competence. The induction of EMT entails the loss of epithelial characteristics and the de novo ac...

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Detalhes bibliográficos
Main Authors: May, Caitlin D, Sphyris, Nathalie, Evans, Kurt W, Werden, Steven J, Guo, Wenjun, Mani, Sendurai A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109556/
https://ncbi.nlm.nih.gov/pubmed/21392411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2789
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