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A novel paramagnetic substrate for detecting myeloperoxidase activity in vivo

Bis-phenylamides and bis-hydroxyindolamides of DTPA(Gd) are paramagnetic reducing substrates of peroxidases that enable molecular imaging of peroxidase activity in vivo. Specifically, bis-5HT-DTPA(Gd) has been used to image localized inflammation in animal models by detecting neutrophil derived myel...

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Bibliografiske detaljer
Main Authors: Shazeeb, Mohammed S., Xie, Yang, Gupta, Suresh, Bogdanov, Alexei A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544410/
https://ncbi.nlm.nih.gov/pubmed/22954188
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