Microsatellite Instability in the Peripheral Blood Leukocytes of HNPCC Patients

Most hereditary nonpolyposis colorectal cancer (HNPCC) patients inherit a defective allele of a mismatch repair (MMR) gene, usually MLH1 or MSH2, resulting in high levels of microsatellite instability (MSIH) in the tumors. Presence of MSI in the normal tissues of mutation carriers has been controver...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Coolbaugh-Murphy, Mary I., Xu, Jing-Ping, Ramagli, Louis S., Ramagli, Brian C., Brown, Barry W., Lynch, Patrick M., Hamilton, Stanley R., Frazier, Marsha L., Siciliano, Michael J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544178/
https://ncbi.nlm.nih.gov/pubmed/20052760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21190
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires