Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet

Type 2 diabetes is associated with obesity, insulin resistance, and inflammation in adipose tissue. 12/15-Lipoxygenase (12/15-LO) generates proinflammatory lipid mediators, which induce inflammation in adipose tissue. Therefore we investigated the role of 12/15-LO activity in mouse white adipose tis...

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Bibliografski detalji
Glavni autori: Cole, Banumathi K., Morris, Margaret A., Grzesik, Wojciech J., Leone, Kendall A., Nadler, Jerry L.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543811/
https://ncbi.nlm.nih.gov/pubmed/23326022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/851798
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