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Simulating realistic genomic data with rare variants

Increasing evidence suggests that rare and generally deleterious genetic variants might have strong impact on disease risks of not only Mendelian disease, but also many common diseases. However, identifying such rare variants remains to be challenging, and novel statistical methods and bioinformatic...

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Hlavní autoři: Xu, Yaji, Wu, Yinghua, Song, Chi, Zhang, Heping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543480/
https://ncbi.nlm.nih.gov/pubmed/23161487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21696
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