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Simulating realistic genomic data with rare variants
Increasing evidence suggests that rare and generally deleterious genetic variants might have strong impact on disease risks of not only Mendelian disease, but also many common diseases. However, identifying such rare variants remains to be challenging, and novel statistical methods and bioinformatic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543480/ https://ncbi.nlm.nih.gov/pubmed/23161487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21696 |
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