Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein

BACKGROUND: Retroviruses HTLV-1 and HTLV-2 have homologous genomic structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell Leukemia (ATL), whereas infection by HTLV-2 has no association with neoplasia. Transformation of T lymphocytes by HTLV-1 is linked to the ca...

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Detalhes bibliográficos
Main Authors: Turci, Marco, Lodewick, Julie, Di Gennaro, Gianfranco, Rinaldi, Anne Sophie, Marin, Oriano, Diani, Erica, Sampaio, Carla, Bex, Françoise, Bertazzoni, Umberto, Romanelli, Maria Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543174/
https://ncbi.nlm.nih.gov/pubmed/23217160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-102
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