Intracellular Localization and Cellular Factors Interaction of HTLV-1 and HTLV-2 Tax Proteins: Similarities and Functional Differences

Human T-lymphotropic viruses type 1 (HTLV-1) and type 2 (HTLV-2) present very similar genomic structures but HTLV-1 is more pathogenic than HTLV-2. Is this difference due to their transactivating Tax proteins, Tax-1 and Tax-2, which are responsible for viral and cellular gene activation? Do Tax-1 an...

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Detalhes bibliográficos
Main Authors: Bertazzoni, Umberto, Turci, Marco, Avesani, Francesca, Di Gennaro, Gianfranco, Bidoia, Carlo, Romanelli, Maria Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185761/
https://ncbi.nlm.nih.gov/pubmed/21994745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v3050541
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