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Pentoxifylline Attenuates Transforming Growth Factor-β1-Stimulated Collagen Deposition and Elastogenesis in Human Tunica Albuginea-Derived Fibroblasts Part 1: Impact on Extracellular Matrix
INTRODUCTION: Transforming growth factor-β1 (TGF-β1) has been implicated in the pathogenesis of Peyronie’s disease (PD) and also plays a role in collagen and elastin metabolism. Pentoxifylline (PTX) antagonizes the effects of TGF-β1 and has been utilized in our clinic for the management of PD. AIM:...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543151/ https://ncbi.nlm.nih.gov/pubmed/20367772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1743-6109.2010.01790.x |
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