Characterization of a Novel α-Conotoxin from Conus textile That Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors

α6β2 Nicotinic acetylcholine receptors (nAChRs) expressed by dopaminergic neurons in the CNS are potential therapeutic targets for the treatment of several neuropsychiatric diseases, including nicotine addiction and Parkinson disease. However, recent studies indicate that the α6 subunit can also ass...

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Hlavní autoři: Luo, Sulan, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, McIntyre, Melissa, Christensen, Sean, Akcan, Muharrem, Craik, David J., McIntosh, J. Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543038/
https://ncbi.nlm.nih.gov/pubmed/23184959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427898
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