Characterization of a Novel α-Conotoxin from Conus textile That Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors

α6β2 Nicotinic acetylcholine receptors (nAChRs) expressed by dopaminergic neurons in the CNS are potential therapeutic targets for the treatment of several neuropsychiatric diseases, including nicotine addiction and Parkinson disease. However, recent studies indicate that the α6 subunit can also ass...

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Main Authors: Luo, Sulan, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, McIntyre, Melissa, Christensen, Sean, Akcan, Muharrem, Craik, David J., McIntosh, J. Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2013
Ábhair:
Protein Structure and Folding
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543038/
https://ncbi.nlm.nih.gov/pubmed/23184959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.427898
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