XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation

Sustained activation of X-box-binding protein 1 (XBP1) results in endothelial cell (EC) apoptosis and atherosclerosis development. The present study provides evidence that XBP1 mRNA splicing triggered an autophagic response in ECs by inducing autophagic vesicle formation and markers of autophagy BEC...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Margariti, Andriana, Li, Hongling, Chen, Ting, Martin, Daniel, Vizcay-Barrena, Gema, Alam, Saydul, Karamariti, Eirini, Xiao, Qingzhong, Zampetaki, Anna, Zhang, Zhongyi, Wang, Wen, Jiang, Zhixin, Gao, Chan, Ma, Benyu, Chen, Ye-Guang, Cockerill, Gillian, Hu, Yanhua, Xu, Qingbo, Zeng, Lingfang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543035/
https://ncbi.nlm.nih.gov/pubmed/23184933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412783
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados