ADAR1 Protein Induces Adenosine-targeted DNA Mutations in Senescent Bcl6 Gene-deficient Cells

Somatic mutations accumulate in senescent cells. Bcl6, which functions as a transcriptional repressor, has been identified as a potent inhibitor of cell senescence, but a role of Bcl6 in the accumulation of somatic mutations has remained unclear. Ig class-switch recombination simultaneously induces...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tsuruoka, Nobuhide, Arima, Masafumi, Yoshida, Nobuya, Okada, Seiji, Sakamoto, Akemi, Hatano, Masahiko, Satake, Hisae, Arguni, Eggi, Wang, Ji-Yang, Yang, Jing-Hua, Nishikura, Kazuko, Sekiya, Souei, Shozu, Makio, Tokuhisa, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543032/
https://ncbi.nlm.nih.gov/pubmed/23209284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365718
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados