Visualization of Structural Changes Accompanying Activation of N-Methyl-d-aspartate (NMDA) Receptors Using Fast-scan Atomic Force Microscopy Imaging

NMDA receptors are widely expressed in the central nervous system and play a major role in excitatory synaptic transmission and plasticity. Here, we used atomic force microscopy (AFM) imaging to visualize activation-induced structural changes in the GluN1/GluN2A NMDA receptor reconstituted into a li...

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Detalhes bibliográficos
Main Authors: Suzuki, Yuki, Goetze, Tom A., Stroebel, David, Balasuriya, Dilshan, Yoshimura, Shige H., Henderson, Robert M., Paoletti, Pierre, Takeyasu, Kunio, Edwardson, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543027/
https://ncbi.nlm.nih.gov/pubmed/23223336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422311
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