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In Vivo Activation of Azipropofol Prolongs Anesthesia and Reveals Synaptic Targets

General anesthetic photolabels have been instrumental in discovering and confirming protein binding partners and binding sites of these promiscuous ligands. We report the in vivo photoactivation of meta-azipropofol, a potent analog of propofol, in Xenopus laevis tadpoles. Covalent adduction of meta-...

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Autori principali: Weiser, Brian P., Kelz, Max B., Eckenhoff, Roderic G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543011/
https://ncbi.nlm.nih.gov/pubmed/23184948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413989
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