Staphylococcus aureus Uses a Novel Multidomain Receptor to Break Apart Human Hemoglobin and Steal Its Heme

Staphylococcus aureus is a leading cause of life-threatening infections in the United States. It requires iron to grow, which must be actively procured from its host to successfully mount an infection. Heme-iron within hemoglobin (Hb) is the most abundant source of iron in the human body and is capt...

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Bibliographic Details
Main Authors: Spirig, Thomas, Malmirchegini, G. Reza, Zhang, Jiang, Robson, Scott A., Sjodt, Megan, Liu, Mengyao, Krishna Kumar, Kaavya, Dickson, Claire F., Gell, David A., Lei, Benfang, Loo, Joseph A., Clubb, Robert T.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542992/
https://ncbi.nlm.nih.gov/pubmed/23132864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419119
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