Ex vivo expansion of normal and chronic myeloid leukemic stem cells without functional alteration using a NUP98HOXA10homeodomain fusion gene

HOX genes have been implicated as regulators of normal and leukemic stem cell functionality, but the extent to which these activities are linked is poorly understood. Previous studies revealed that transduction of primitive mouse hematopoietic cells with a NUP98HOXA10homeodomain (NA10HD) fusion gene...

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Main Authors: Sloma, I, Imren, S, Beer, P A, Zhao, Y, Lecault, V, Leung, D, Raghuram, K, Brimacombe, C, Lambie, K, Piret, J, Hansen, C, Humphries, R K, Eaves, C J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542630/
https://ncbi.nlm.nih.gov/pubmed/22868969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.196
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