Chromosome anomalies in bone marrow as primary cause of aplastic or hypoplastic conditions and peripheral cytopenia: disorders due to secondary impairment of RUNX1 and MPL genes

BACKGROUND: Chromosome changes in the bone marrow (BM) of patients with persistent cytopenia are often considered diagnostic for a myelodysplastic syndrome (MDS). Comprehensive cytogenetic evaluations may give evidence of the real pathogenetic role of these changes in cases with cytopenia without mo...

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Detalhes bibliográficos
Main Authors: Marletta, Cristina, Valli, Roberto, Pressato, Barbara, Mare, Lydia, Montalbano, Giuseppe, Menna, Giuseppe, Loffredo, Giuseppe, Bernardo, Maria Ester, Vinti, Luciana, Ferrari, Simona, Di Cesare-Merlone, Alessandra, Zecca, Marco, Lo Curto, Francesco, Locatelli, Franco, Pasquali, Francesco, Maserati, Emanuela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542585/
https://ncbi.nlm.nih.gov/pubmed/23025896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-5-39
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