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A Tight Link between Orthologs and Bidirectional Best Hits in Bacterial and Archaeal Genomes

Orthologous relationships between genes are routinely inferred from bidirectional best hits (BBH) in pairwise genome comparisons. However, to our knowledge, it has never been quantitatively demonstrated that orthologs form BBH. To test this “BBH-orthology conjecture,” we take advantage of the operon...

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Hlavní autoři: Wolf, Yuri I., Koonin, Eugene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542571/
https://ncbi.nlm.nih.gov/pubmed/23160176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evs100
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