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A Tight Link between Orthologs and Bidirectional Best Hits in Bacterial and Archaeal Genomes

Orthologous relationships between genes are routinely inferred from bidirectional best hits (BBH) in pairwise genome comparisons. However, to our knowledge, it has never been quantitatively demonstrated that orthologs form BBH. To test this “BBH-orthology conjecture,” we take advantage of the operon...

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Detalhes bibliográficos
Main Authors: Wolf, Yuri I., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542571/
https://ncbi.nlm.nih.gov/pubmed/23160176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evs100
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