Birth-and-Death of KLK3 and KLK2 in Primates: Evolution Driven by Reproductive Biology

The kallikrein (KLK) gene family comprises the largest uninterrupted locus of serine proteases in the human genome and represents a notable case for studying the evolutionary fate of duplicated genes. In primates, a recent duplication event gave rise to KLK2 and KLK3, both encoding essential protein...

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Detalhes bibliográficos
Main Authors: Marques, Patrícia Isabel, Bernardino, Rui, Fernandes, Teresa, Green, Eric D., Hurle, Belen, Quesada, Victor, Seixas, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542562/
https://ncbi.nlm.nih.gov/pubmed/23204305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evs111
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