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A mechanism for robust circadian timekeeping via stoichiometric balance

Circadian (∼24 h) timekeeping is essential for the lives of many organisms. To understand the biochemical mechanisms of this timekeeping, we have developed a detailed mathematical model of the mammalian circadian clock. Our model can accurately predict diverse experimental data including the phenoty...

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Detalhes bibliográficos
Main Authors: Kim, Jae Kyoung, Forger, Daniel B
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542529/
https://ncbi.nlm.nih.gov/pubmed/23212247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.62
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