Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumors

Schwannomas are peripheral nerve sheath tumors that often occur in the setting of an inherited tumor predisposition syndrome, including Neurofibromatosis Types 1 (NF1) and 2 (NF2), Familial Schwannomatosis (FS) and Carney Complex (CNC). Loss of the NF2 tumor suppressor (encoding NF2, or Merlin) is a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Manchanda, Parmeet K., Jones, Georgette N., Lee, Audrey A., Pringle, Daphne R., Zhang, Mei, Yu, Lianbo, La Perle, Krista M. D., Kirschner, Lawrence S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542412/
https://ncbi.nlm.nih.gov/pubmed/23045281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.374
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