Histone Deacetylase Inhibition Decreases Cholesterol Levels in Neuronal Cells by Modulating Key Genes in Cholesterol Synthesis, Uptake and Efflux

Cholesterol is an essential component of the central nervous system and increasing evidence suggests an association between brain cholesterol metabolism dysfunction and the onset of neurodegenerative disorders. Interestingly, histone deacetylase inhibitors (HDACi) such as trichostatin A (TSA) are em...

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Detaylı Bibliyografya
Asıl Yazarlar: Nunes, Maria João, Moutinho, Miguel, Gama, Maria João, Rodrigues, Cecília M. P., Rodrigues, Elsa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542332/
https://ncbi.nlm.nih.gov/pubmed/23326422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053394
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