X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer

BACKGROUND: Histone deacetylase (HDAC) plays an important role in the deacetylation of histone, which can alter gene expression patterns and affect cell behavior associated with malignant transformation. The aims of this study were to investigate the relationships between HDAC1, HDAC2, clinicopathol...

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Hauptverfasser: Han, Yang, Zhang, Yong, Yang, Lian-he, Mi, Xiao-yi, Dai, Shun-dong, Li, Qing-chang, Xu, Hong-tao, Yu, Juan-han, Li, Guang, Zhao, Jing, Han, Chong, Yuan, Xi-ming, Wang, En-hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542190/
https://ncbi.nlm.nih.gov/pubmed/23110995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-183
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