Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib

About 20% to 40% of patients with non-small cell lung cancer (NSCLC) will develop brain metastases during the natural course of their disease. The prognosis for such patients is very poor with limited survival. In addition to the standard whole brain radiation therapy (WBRT), some studies have shown...

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Autores principales: Yuan, Ying, Tan, Chunwen, Li, Modan, Shen, Hong, Fang, Xuefeng, Hu, Yinghong, Ma, Shenglin
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542167/
https://ncbi.nlm.nih.gov/pubmed/23134665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-10-235
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