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Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib

About 20% to 40% of patients with non-small cell lung cancer (NSCLC) will develop brain metastases during the natural course of their disease. The prognosis for such patients is very poor with limited survival. In addition to the standard whole brain radiation therapy (WBRT), some studies have shown...

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Detalhes bibliográficos
Main Authors: Yuan, Ying, Tan, Chunwen, Li, Modan, Shen, Hong, Fang, Xuefeng, Hu, Yinghong, Ma, Shenglin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542167/
https://ncbi.nlm.nih.gov/pubmed/23134665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-10-235
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