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Evolution of the hepatitis E virus hypervariable region

The presence of a hypervariable (HVR) region within the genome of hepatitis E virus (HEV) remains unexplained. Previous studies have described the HVR as a proline-rich spacer between flanking functional domains of the ORF1 polyprotein. Others have proposed that the region has no function, that it r...

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Autors principals: Smith, Donald B., Vanek, Jeff, Ramalingam, Sandeep, Johannessen, Ingolfur, Templeton, Kate, Simmonds, Peter
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542125/
https://ncbi.nlm.nih.gov/pubmed/22837418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.045351-0
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