Evolution of Hepatitis C Virus Quasispecies in Hypervariable Region 1 and the Putative Interferon Sensitivity-Determining Region during Interferon Therapy and Natural Infection

To study hepatitis C virus (HCV) genetic mutation during interferon (IFN) therapy, the temporal changes in HCV quasispecies heterogeneity were compared before and after treatment for nine patients infected with HCV genotype 1, including four nonresponders, four responders who relapsed after therapy,...

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Detalhes bibliográficos
Main Authors: Polyak, Stephen J., McArdle, Susan, Liu, Shan-Lu, Sullivan, Daniel G., Chung, Minjun, Hofgärtner, Wolfgang T., Carithers, Robert L., McMahon, Brian J., Mullins, James I., Corey, Lawrence, Gretch, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Animal Viruses
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109659/
https://ncbi.nlm.nih.gov/pubmed/9557719
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