Evolution of Hepatitis C Virus Quasispecies in Hypervariable Region 1 and the Putative Interferon Sensitivity-Determining Region during Interferon Therapy and Natural Infection

To study hepatitis C virus (HCV) genetic mutation during interferon (IFN) therapy, the temporal changes in HCV quasispecies heterogeneity were compared before and after treatment for nine patients infected with HCV genotype 1, including four nonresponders, four responders who relapsed after therapy,...

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Bibliographische Detailangaben
Hauptverfasser: Polyak, Stephen J., McArdle, Susan, Liu, Shan-Lu, Sullivan, Daniel G., Chung, Minjun, Hofgärtner, Wolfgang T., Carithers, Robert L., McMahon, Brian J., Mullins, James I., Corey, Lawrence, Gretch, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Animal Viruses
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109659/
https://ncbi.nlm.nih.gov/pubmed/9557719
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