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Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function

RNA-binding proteins CUG-binding protein 1 (CUGBP1) and HuR are highly expressed in epithelial tissues and modulate the stability and translation of target mRNAs. Here we present evidence that CUGBP1 and HuR jointly regulate the translation of occludin and play a crucial role in the maintenance of t...

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Bibliografski detalji
Glavni autori: Yu, Ting-Xi, Rao, Jaladanki N., Zou, Tongtong, Liu, Lan, Xiao, Lan, Ouyang, Miao, Cao, Shan, Gorospe, Myriam, Wang, Jian-Ying
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541967/
https://ncbi.nlm.nih.gov/pubmed/23155001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0531
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