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Enrichment of Associations in Genes with Fibrosis, Apoptosis, and Innate Immunity Functions with Cardiac Manifestation of Neonatal Lupus

OBJECTIVE: The proposed pathogenesis of the cardiac manifestations of neonatal lupus (cardiac-NL) involves maternal autoantibodies to the ribonucleoproteins SSA/Ro and SSB/La enhanced by as yet unknown factors likely to involve the dysregulation of both inflammatory and fibrotic fetal responses. Thi...

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Autori principali: Ramos, Paula S., Marion, Miranda C., Langefeld, Carl D., Buyon, Jill P., Clancy, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541680/
https://ncbi.nlm.nih.gov/pubmed/22886516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34663
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