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Preferential Transmission of Genetic Risk Variants of Candidate Loci at 6p21 from Asymptomatic Grandparents to Mothers of Children with Neonatal Lupus

BACKGROUND: Neonatal lupus (NL) occurs in fetuses exposed to maternal anti-SSA/Ro and/or SSB/La antibodies, although the mothers may not manifest any clinical disease. A focus on transmission of risk factors for NL from maternal grandparents to mothers may yield dividends towards understanding the a...

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Detalhes bibliográficos
Main Authors: Saxena, Amit, McDonnell, Erin, Ramos, Paula S., Sajuthi, Satria, Marion, Miranda C., Langefeld, Carl D., Buyon, Jill P., Clancy, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270151/
https://ncbi.nlm.nih.gov/pubmed/22031281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33366
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