Arterial Retention of Remnant Lipoproteins Ex Vivo Is Increased in Insulin Resistance Because of Increased Arterial Biglycan and Production of Cholesterol-Rich Atherogenic Particles That Can Be Improved by Ezetimibe in the JCR:LA-cp Rat

BACKGROUND: Literature supports the “response-to-retention” hypothesis—that during insulin resistance, impaired metabolism of remnant lipoproteins can contribute to accelerated cardiovascular disease progression. We used the JCR:LA-cp rat model of metabolic syndrome (MetS) to determine the extent of...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Mangat, Rabban, Warnakula, Samantha, Borthwick, Faye, Hassanali, Zahra, Uwiera, Richard R.E., Russell, James C., Cheeseman, Christopher I., Vine, Donna F., Proctor, Spencer D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541624/
https://ncbi.nlm.nih.gov/pubmed/23316299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.003434
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky