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Photochemical addition of the cross-linking reagent 4,5', 8-trimethylpsoralen (trioxaslen) to intracellular and viral simian virus 40 DNA-histone complexes.

We demonstrated here that 4,5', 8-trimethylpsoralen (trioxsalen) is a valuable probe for the structure of SV40 DNA-histone complexes. Trioxsalen readily penetrated intact cells and, in the presence of 340- to 380-nm light, covalently cross-linked DNA preferentially at the sites available for mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Hallick, L M, Yokota, H A, Bartholomew, J C, Hearst, J E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1978
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC354146/
https://ncbi.nlm.nih.gov/pubmed/211247
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