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Photochemical addition of the cross-linking reagent 4,5', 8-trimethylpsoralen (trioxaslen) to intracellular and viral simian virus 40 DNA-histone complexes.

We demonstrated here that 4,5', 8-trimethylpsoralen (trioxsalen) is a valuable probe for the structure of SV40 DNA-histone complexes. Trioxsalen readily penetrated intact cells and, in the presence of 340- to 380-nm light, covalently cross-linked DNA preferentially at the sites available for microco...

Täydet tiedot

Tallennettuna:
Julkaisussa:J Virol
Päätekijät: Hallick, L M, Yokota, H A, Bartholomew, J C, Hearst, J E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1978
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC354146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/211247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.27.1.127-135.1978
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