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Host immune system strikes back: Autophagy-mediated antigen presentation bypasses viral blockade of the classic MHC class I processing pathway

Autophagy-mediated major histocompatibility complex (MHC) class I presentation can follow either the conventional MHC class I pathway or a recently described vacuolar pathway. In the vacuolar pathway, protein degradation is effected by lysosomal proteases, peptide exchange takes place with recircula...

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Autors principals: Tey, Siok-Keen, Khanna, Rajiv
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541298/
https://ncbi.nlm.nih.gov/pubmed/22932396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21860
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