Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation

Although it is known that tumor necrosis factor-related apoptosis-inducing ligand (TNFSF10/TRAIL) induces autophagy, the mechanism by which autophagy is activated by TNFSF10 is still elusive. In this report, we show evidence that TRAF2- and RIPK1-mediated MAPK8/JNK activation is required for TNFSF10...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: He, Weiyang, Wang, Qiong, Xu, Jennings, Xu, Xiuling, Padilla, Mabel T., Ren, Guosheng, Gou, Xin, Lin, Yong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2012
Aiheet:
Basic Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541290/
https://ncbi.nlm.nih.gov/pubmed/23051914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22145
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