In vitro and in vivo characterization of DNA delivery using recombinant Lactococcus lactis expressing a mutated form of L. monocytogenes Internalin A

BACKGROUND: The use of food-grade Lactic Acid Bacteria (LAB) as DNA delivery vehicles represents an attractive strategy to deliver DNA vaccines at the mucosal surfaces as they are generally regarded as safe (GRAS). We previously showed that either native Lactococcus lactis (LL) or recombinant invasi...

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Detalhes bibliográficos
Main Authors: de Azevedo, Marcela, Karczewski, Jurgen, Lefévre, François, Azevedo, Vasco, Miyoshi, Anderson, Wells, Jerry M, Langella, Philippe, Chatel, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541092/
https://ncbi.nlm.nih.gov/pubmed/23253484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-12-299
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