Aiolos promotes T(H)17 differentiation by directly silencing Il2 expression

CD4(+) interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) are instrumental in the immune response to pathogens. However, an overactive T(H)17 response results in tissue inflammation and autoimmunity, and therefore it is important to identify the molecular mechanisms that control the deve...

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Detalhes bibliográficos
Main Authors: Quintana, Francisco J, Jin, Hulin, Burns, Evan J, Nadeau, Meghan, Yeste, Ada, Kumar, Deepak, Rangachari, Manu, Zhu, Chen, Xiao, Sheng, Seavitt, John, Georgopoulos, Katia, Kuchroo, Vijay K
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541018/
https://ncbi.nlm.nih.gov/pubmed/22751139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2363
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