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T helper-1 cell induction in lymph nodes according to a red – blue chemokine map

Lymph nodes are compartmentalized organs but whether this feature has a role in T cell differentiation has been unclear. In this issue, Groom et al (Immunity 2012) reveal that spatially separated expression of two CXCR3 ligands guides Th1 cell development.

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Hlavní autoři: Matloubian, Mehrdad, Cyster, Jason G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540980/
https://ncbi.nlm.nih.gov/pubmed/23244716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.11.007
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