CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4(+) T helper 1 cell differentiation

Differentiation of naïve CD4(+) T cells into T helper (T(h)) cells is a defining event in adaptive immunity. The cytokines and transcription factors that control Th cell differentiation are understood, however it is not known how this process is orchestrated within lymph nodes (LNs). Here we have sh...

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Bibliographische Detailangaben
Hauptverfasser: Groom, Joanna R., Richmond, Jillian, Murooka, Thomas T., Sorensen, Elizabeth W., Sung, Jung Hwan, Bankert, Katherine, von Andrian, Ulrich H., Moon, James J., Mempel, Thorsten R., Luster, Andrew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525757/
https://ncbi.nlm.nih.gov/pubmed/23123063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.08.016
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