Nicotine Induces Inhibitor of Differentiation-1 in a Src-dependent Pathway Promoting Metastasis and Chemoresistance in Pancreatic Adenocarcinoma

Smoking is a significant risk factor for pancreatic cancer, but the molecular mechanisms by which tobacco smoke components promote the growth and progression of these cancers are not fully understood. While nicotine, the addictive component of tobacco smoke, is not a carcinogen, it has been shown to...

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Bibliographic Details
Main Authors: Trevino, Jose G, Pillai, Smitha, Kunigal, Sateesh, Singh, Sandeep, Fulp, William J, Centeno, Barbara A, Chellappan, Srikumar P
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540937/
https://ncbi.nlm.nih.gov/pubmed/23308043
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