Nicotine Induces Inhibitor of Differentiation-1 in a Src-dependent Pathway Promoting Metastasis and Chemoresistance in Pancreatic Adenocarcinoma

Smoking is a significant risk factor for pancreatic cancer, but the molecular mechanisms by which tobacco smoke components promote the growth and progression of these cancers are not fully understood. While nicotine, the addictive component of tobacco smoke, is not a carcinogen, it has been shown to...

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Autores principales: Trevino, Jose G, Pillai, Smitha, Kunigal, Sateesh, Singh, Sandeep, Fulp, William J, Centeno, Barbara A, Chellappan, Srikumar P
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540937/
https://ncbi.nlm.nih.gov/pubmed/23308043
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