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Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag)

Ubiquitination appears to be involved in virus particle release from infected cells. Free ubiquitin (Ub), as well as Ub covalently bound to a small fraction of p6 Gag, is detected in mature HIV particles. Here we report that the p6 region in the Pr55(Gag) structural precursor polyprotein binds to Ts...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: VerPlank, Lynn, Bouamr, Fadila, LaGrassa, Tracy J., Agresta, Beth, Kikonyogo, Alexandra, Leis, Jonathan, Carter, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35409/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11427703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.131059198
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