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Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)
The apical Na(+)-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt structure during evolution. We characterized...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540847/ https://ncbi.nlm.nih.gov/pubmed/22669917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M025726 |
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